Articles Tagged With:
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Disorders of Immunity Are a Risk Factor for Herpes Simplex Virus Encephalitis
The current study of herpes simplex virus (HSV) encephalitis demonstrated an association of encephalitis with preexisting autoimmune disease and/or exposure to immunosuppressive and immunomodulatory medications. The findings underscore the potential underestimation of antecedent immune-related dysregulation in HSV encephalitis cases to date.
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Efgartigimod for Seronegative Myasthenia Gravis
In an uncontrolled, open-label series of patients with myasthenia gravis, double antibody-negative patients responded to immunosuppressive therapies in a similar manner as do those with antibodies to acetylcholine receptors (AChR) or muscle-specific tyrosine kinase. However, when treating myasthenia patients with a specific agent (efgartigimod) that blocks AChR antibodies at the level of endothelial cells, double antibody-negative patients do not respond as well.
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Usefulness of the Physical Examination in the Concussed Patient
This article suggests that certain specific physical examination findings may be helpful in evaluating and monitoring patients with sports-related concussion using oculovestibular responses and balance tests.
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Intensive Lifestyle Interventions May Prevent and Ameliorate the Symptoms of Alzheimer’s Disease
Recent clinical studies support the benefit of intensive lifestyle interventions, which should include a plant-based diet, exercise, stress management, and avoidance of smoking and alcohol, for the prevention of Alzheimer’s disease.
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Non-Marine Envenomations in the United States
Envenomations can be caused by many different species, both marine and non-marine. The presentation can range from minor skin irritation to anaphylaxis, systemic illness, organ failure, and even death. Knowing which species are endemic to the area, and what the presentations of medically important envenomations will look like, can aid in recognition and timely treatment, especially when the bite or sting was unwitnessed. This article will give an overview of medically important non-marine envenomations in the United States, including their clinical manifestations, treatment, and disposition.
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Doxycycline After Sex
Single-dose doxycycline is recommended after oral, vaginal, or anal sex in selected high-risk individuals.
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Cefepime and Enmetazobactam Injection (Exblifep)
The U.S. Food and Drug Administration has approved the combination of cefepime and enmetazobactam (FPE) for the treatment of complicated urinary tract infections (cUTIs).
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Summer Travel: News Clinicians (and Their Patients) Can Use
New science can guide us as we and our patients travel this season. Now, Infectious Disease Alert briefly reviews 13 new and in-press papers from the two main travel medicine journals.
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Does Paxlovid Help in Patients with Long COVID?
Paxlovid treatment of adults with post-acute sequelae of SARS-CoV-2 infection — also known as long COVID — was ineffective in a randomized controlled trial.
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Treatment of Invasive Aspergillosis in Solid Organ Transplant Recipients: Isavuconazole or Voriconazole?
An analysis of two retrospective cohort studies of solid organ transplant recipients with invasive aspergillosis found that isavuconazole and voriconazole had similar efficacy, but isavuconazole was better tolerated.